Managing diabetes with inhaled insulin

Inhaled insulin in diabetes mellitus.

BACKGROUND Insulin therapy often relies on multiple daily injections of insulin. However this is a considerable burden to many people with diabetes and adherence to such an insulin regimen can be difficult to maintain, hence compromising optimal glycaemic control. Also, short acting injected insulin is absorbed more slowly than insulin released by the normal pancreas in response to a meal. Inha...

Inhaled insulin for controlling blood glucose in patients with diabetes

Diabetes mellitus is a significant worldwide health problem, with the incidence of type 2 diabetes increasing at alarming rates. Insulin resistance and dysregulated blood glucose control are established risk factors for microvascular complications and cardiovascular disease. Despite the recognition of diabetes as a major health issue and the availability of a growing number of medications desig...

Overall satisfaction increased more with inhaled insulin than with subcutaneous insulin in type 1 diabetes.

Type 3 diabetes mellitus. The revival of inhaled insulin?

Type 2 diabetes mellitus (DM) and dementia are two conditions highly prevalent today and probably interrelated. The term type 3 diabetes has therefore been proposed to try and provide a view integrating the potential pathogenetic mechanisms shared by DM and Alzheimer disease (AD). Significant epidemiological evidence relating DM and dementia has accumulated in the past decade. According to a re...

Inhaled Formoterol Diminishes Insulin-Induced Hypoglycemia in Type 1 Diabetes

OBJECTIVE Hypoglycemia is one of the major factors limiting implementation of tight glycemic control in patients with type 1 diabetes and is associated with increased morbidity and mortality during intensive insulin treatment. β-2 Adrenergic receptor (AR) agonists have been reported to diminish nocturnal hypoglycemia; however, whether long-acting inhaled β-2 AR agonists could potentially be use...